diff --git a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationDiagnosisAppServiceImpl.java b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationDiagnosisAppServiceImpl.java
index 3e9d2aa54..d36440d28 100755
--- a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationDiagnosisAppServiceImpl.java
+++ b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationDiagnosisAppServiceImpl.java
@@ -580,7 +580,11 @@ public class DoctorStationDiagnosisAppServiceImpl implements IDoctorStationDiagn
     @Override
     public R<?> saveInfectiousDiseaseReport(InfectiousDiseaseReportDto infectiousDiseaseReportDto) {
         // 检查卡片编号唯一性（新增时检查，编辑时排除当前记录）
-        String cardNo = infectiousDiseaseReportDto.getCardNo().trim();
+        String cardNo = infectiousDiseaseReportDto.getCardNo();
+        if (cardNo == null || cardNo.trim().isEmpty()) {
+            return R.fail("卡片编号不能为空");
+        }
+        cardNo = cardNo.trim();
         LambdaQueryWrapper<InfectiousDiseaseReport> queryWrapper = new LambdaQueryWrapper<>();
         queryWrapper.eq(InfectiousDiseaseReport::getCardNo, cardNo);
         long count = iInfectiousDiseaseReportService.count(queryWrapper);
diff --git a/openhis-ui-vue3/src/views/doctorstation/components/diagnosis/infectiousDiseaseReportDialog.vue b/openhis-ui-vue3/src/views/doctorstation/components/diagnosis/infectiousDiseaseReportDialog.vue
index 867e382b5..71990e8d5 100755
--- a/openhis-ui-vue3/src/views/doctorstation/components/diagnosis/infectiousDiseaseReportDialog.vue
+++ b/openhis-ui-vue3/src/views/doctorstation/components/diagnosis/infectiousDiseaseReportDialog.vue
@@ -1366,6 +1366,9 @@ async function buildSubmitData() {
   } else if (formData.otherDisease) {
     // 其他传染病使用自定义编码
     diseaseCode = 'OTHER';
+  } else if (formData.selectedDiseases && formData.selectedDiseases.length > 0) {
+    // 兜底：如果 ClassA/B/C 都为空但 selectedDiseases 有值，取第一个作为 diseaseCode
+    diseaseCode = formData.selectedDiseases[0];
   }
 
   // 转换年龄单位：岁=1, 月=2, 天=3