diff --git a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/utils/AdviceUtils.java b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/utils/AdviceUtils.java
index 5e4e9c28..6dccd820 100755
--- a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/utils/AdviceUtils.java
+++ b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/utils/AdviceUtils.java
@@ -83,9 +83,14 @@ public class AdviceUtils {
      * @return 提示信息
      */
     public String checkInventory(List<AdviceSaveDto> adviceSaveList) {
-        // 医嘱定义ID集合
+        // 医嘱定义ID集合（过滤null值，避免SQL查询异常）
         List<Long> adviceDefinitionIdList
-                = adviceSaveList.stream().map(AdviceSaveDto::getAdviceDefinitionId).collect(Collectors.toList());
+                = adviceSaveList.stream().map(AdviceSaveDto::getAdviceDefinitionId)
+                .filter(id -> id != null).collect(Collectors.toList());
+        // 🔧 Bug #504 修复：如果所有adviceDefinitionId都为null，跳过库存校验
+        if (adviceDefinitionIdList.isEmpty()) {
+            return null;
+        }
         // 医嘱库存集合
         List<AdviceInventoryDto> adviceInventoryList
                 = doctorStationAdviceAppMapper.getAdviceInventory(null, adviceDefinitionIdList,
@@ -99,6 +104,10 @@ public class AdviceUtils {
                 = this.subtractInventory(adviceInventoryList, adviceDraftInventoryList);
         // 检查库存
         for (AdviceSaveDto saveDto : adviceSaveList) {
+            // 🔧 Bug #504 修复：退回医嘱可能adviceDefinitionId为空，跳过校验
+            if (saveDto.getAdviceDefinitionId() == null) {
+                continue;
+            }
             boolean matched = false;
             for (AdviceInventoryDto inventoryDto : adviceInventory) {
                 // 匹配条件：adviceDefinitionId, adviceTableName, locationId, lotNumber 同时相等
@@ -108,10 +117,12 @@ public class AdviceUtils {
                         || saveDto.getLotNumber().equals(inventoryDto.getLotNumber());
                 boolean tableNameMatch = StringUtils.isEmpty(saveDto.getAdviceTableName())
                         || inventoryDto.getItemTable().equals(saveDto.getAdviceTableName());
-//                if (saveDto.)
+                // 🔧 Bug #504 修复：退回医嘱可能locationId为空，跳过location匹配
+                boolean locationMatch = saveDto.getLocationId() == null
+                        || inventoryDto.getLocationId().equals(saveDto.getLocationId());
                 if (inventoryDto.getItemId().equals(saveDto.getAdviceDefinitionId())
                         && tableNameMatch
-                        && inventoryDto.getLocationId().equals(saveDto.getLocationId()) && lotNumberMatch) {
+                        && locationMatch && lotNumberMatch) {
                     matched = true;
                     // 检查库存是否充足
                     BigDecimal minUnitQuantity = saveDto.getMinUnitQuantity();
diff --git a/openhis-server-new/openhis-application/src/main/resources/mapper/regdoctorstation/AdviceManageAppMapper.xml b/openhis-server-new/openhis-application/src/main/resources/mapper/regdoctorstation/AdviceManageAppMapper.xml
index c5d06303..4be9c705 100755
--- a/openhis-server-new/openhis-application/src/main/resources/mapper/regdoctorstation/AdviceManageAppMapper.xml
+++ b/openhis-server-new/openhis-application/src/main/resources/mapper/regdoctorstation/AdviceManageAppMapper.xml
@@ -216,7 +216,8 @@
         ccd.name AS condition_definition_name,
         T1.therapy_enum AS therapyEnum,
         T1.sort_number AS sort_number,
-        T1.based_on_id AS based_on_id
+        T1.based_on_id AS based_on_id,
+        T1.medication_id AS advice_definition_id
         FROM med_medication_request AS T1
         LEFT JOIN med_medication_definition AS T2 ON T2.ID = T1.medication_id
         AND T2.delete_flag = '0'
@@ -268,7 +269,8 @@
         '' AS condition_definition_name,
         2 AS therapyEnum,
         99 AS sort_number,
-        T1.based_on_id AS based_on_id
+        T1.based_on_id AS based_on_id,
+        T1.device_def_id AS advice_definition_id
         FROM wor_device_request AS T1
         LEFT JOIN adm_device_definition AS T2 ON T2.ID = T1.device_def_id
         AND T2.delete_flag = '0'
@@ -317,7 +319,8 @@
         '' AS condition_definition_name,
         COALESCE(T1.therapy_enum, 2) AS therapyEnum,
         99 AS sort_number,
-        T1.based_on_id AS based_on_id
+        T1.based_on_id AS based_on_id,
+        T1.activity_id AS advice_definition_id
         FROM wor_service_request AS T1
         LEFT JOIN wor_activity_definition AS T2
         ON T2.ID = T1.activity_id