diff --git a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java
index a95f8d971..51b0b6f12 100755
--- a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java
+++ b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java
@@ -582,7 +582,10 @@ public class AdviceProcessAppServiceImpl implements IAdviceProcessAppService {
         // 处理长期已发放的药品
         if (!longMedDispensedList.isEmpty()) {
             // 生成退药单
-            this.creatRefundMedicationList(tempMedDispensedList, procedureIdMap);
+            this.creatRefundMedicationList(longMedDispensedList, procedureIdMap);
+            // 药品退药请求状态变更(待退药)
+            medicationRequestService.updateCancelledStatusBatch(
+                    longMedDispensedList.stream().map(MedicationDispense::getMedReqId).toList(), null, null);
         }
         // 处理临时已发放药品
         if (!tempMedDispensedList.isEmpty()) {
diff --git a/openhis-ui-vue3/src/views/inpatientNurse/medicalOrderExecution/index.vue b/openhis-ui-vue3/src/views/inpatientNurse/medicalOrderExecution/index.vue
index af7f25ae3..18318b138 100755
--- a/openhis-ui-vue3/src/views/inpatientNurse/medicalOrderExecution/index.vue
+++ b/openhis-ui-vue3/src/views/inpatientNurse/medicalOrderExecution/index.vue
@@ -111,6 +111,7 @@ function handleClick(tabName) {
       break;
     case 'cancel':
       exeStatus.value = 9;
+      requestStatus.value = RequestStatus.CANCELLED;
       break;
   }