diff --git a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationAdviceAppServiceImpl.java b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationAdviceAppServiceImpl.java
index 5c9ab5d49..f50c30307 100755
--- a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationAdviceAppServiceImpl.java
+++ b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/doctorstation/appservice/impl/DoctorStationAdviceAppServiceImpl.java
@@ -1539,11 +1539,22 @@ public class DoctorStationAdviceAppServiceImpl implements IDoctorStationAdviceAp
             deviceRequest.setRequesterId(adviceSaveDto.getPractitionerId()); // 开方医生
             deviceRequest.setOrgId(adviceSaveDto.getFounderOrgId());// 开方人科室
             deviceRequest.setReqAuthoredTime(curDate); // 请求开始时间
-            // 发放耗材房（若前端未传locationId，使用登录用户的科室作为默认值）
+            // 发放耗材房（若前端未传locationId，优先沿用已有DeviceRequest的performLocation，否则使用登录用户科室）
             Long locId = adviceSaveDto.getLocationId();
             if (locId == null) {
-                locId = SecurityUtils.getLoginUser().getOrgId();
-                log.info("耗材locationId为空，使用登录用户科室作为默认值: locationId={}", locId);
+                // 尝试从已有DeviceRequest获取原始的performLocation
+                if (adviceSaveDto.getRequestId() != null) {
+                    DeviceRequest existingDevice = iDeviceRequestService.getById(adviceSaveDto.getRequestId());
+                    if (existingDevice != null && existingDevice.getPerformLocation() != null) {
+                        locId = existingDevice.getPerformLocation();
+                        log.info("耗材locationId为空，使用已有DeviceRequest的performLocation: locationId={}", locId);
+                    }
+                }
+                // 如果已有记录也没有performLocation，则使用登录用户科室作为兜底
+                if (locId == null) {
+                    locId = SecurityUtils.getLoginUser().getOrgId();
+                    log.info("耗材locationId为空且无已有记录，使用登录用户科室作为默认值: locationId={}", locId);
+                }
             }
             deviceRequest.setPerformLocation(locId);
             deviceRequest.setEncounterId(adviceSaveDto.getEncounterId()); // 就诊id
diff --git a/openhis-ui-vue3/src/views/clinicmanagement/bargain/component/prescriptionlist.vue b/openhis-ui-vue3/src/views/clinicmanagement/bargain/component/prescriptionlist.vue
index 5fcfe6cc1..709e4303c 100755
--- a/openhis-ui-vue3/src/views/clinicmanagement/bargain/component/prescriptionlist.vue
+++ b/openhis-ui-vue3/src/views/clinicmanagement/bargain/component/prescriptionlist.vue
@@ -1036,6 +1036,14 @@ function handleSave() {
       requestId: item.requestId,
       dbOpType: '1',
       groupId: item.groupId,
+      // 🔧 Bug #443: 补充顶层关键字段（这些不在 contentJson 中，需从 API 响应顶层提取）
+      encounterId: item.encounterId,
+      patientId: item.patientId,
+      locationId: item.positionId,
+      adviceType: item.adviceType,
+      adviceTableName: item.adviceTableName,
+      adviceDefinitionId: item.adviceDefinitionId,
+      chargeItemId: item.chargeItemId,
     };
   });
   savePrescriptionSign({