diff --git a/openhis-ui-vue3/src/views/doctorstation/components/inspection/inspectionApplication.vue b/openhis-ui-vue3/src/views/doctorstation/components/inspection/inspectionApplication.vue
index 6e17e4f1..43cd7344 100755
--- a/openhis-ui-vue3/src/views/doctorstation/components/inspection/inspectionApplication.vue
+++ b/openhis-ui-vue3/src/views/doctorstation/components/inspection/inspectionApplication.vue
@@ -2063,15 +2063,20 @@ watch(() => props.patientInfo, async (newVal) => {
   }
 }, { deep: true, immediate: true })
 
-// Bug #329: 监听已选择的检验项目，自动更新检验项目文本并设置默认执行科室
+// Bug #329/#466: 监听已选择的检验项目，自动更新检验项目文本并设置默认执行科室、标本类型
 watch(() => selectedInspectionItems.value, async (newVal) => {
   if (newVal && newVal.length > 0) {
     formData.inspectionItemsText = newVal.map(item => item.itemName).join('+')
 
+    const firstItem = newVal[0]
+
+    // Bug #466: 如果标本类型为空或仍为初始化默认值，根据第一个检验项目的 sampleType 自动设置默认标本类型
+    if ((!formData.specimenName || formData.specimenName === '血液') && firstItem.sampleType) {
+      formData.specimenName = firstItem.sampleType
+    }
+
     // Bug #329: 如果执行科室为空，根据第一个检验项目的检验类型自动设置默认执行科室
     if (!formData.executeDepartment) {
-      const firstItem = newVal[0]
-
       // 根据检验项目的 inspectionTypeId 获取默认执行科室
       if (firstItem.inspectionTypeId) {
         const defaultDeptCode = await getDefaultPerformDeptCode(firstItem.inspectionTypeId)
@@ -2081,9 +2086,10 @@ watch(() => selectedInspectionItems.value, async (newVal) => {
       }
     }
   } else {
-    // Bug #329: 当项目被清空时，同时清空执行科室（下次选择项目时会重新自动设置）
+    // Bug #329: 当项目被清空时，同时清空执行科室和标本类型（下次选择项目时会重新自动设置）
     formData.inspectionItemsText = ''
     formData.executeDepartment = ''
+    formData.specimenName = ''
   }
 }, { deep: true })