diff --git a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java
index d146e5b2..95061f5f 100755
--- a/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java
+++ b/openhis-server-new/openhis-application/src/main/java/com/openhis/web/inhospitalnursestation/appservice/impl/AdviceProcessAppServiceImpl.java
@@ -7,6 +7,7 @@ import com.baomidou.mybatisplus.core.conditions.query.LambdaQueryWrapper;
 import com.baomidou.mybatisplus.core.conditions.query.QueryWrapper;
 import com.baomidou.mybatisplus.core.conditions.update.LambdaUpdateWrapper;
 import com.baomidou.mybatisplus.extension.plugins.pagination.Page;
+import org.springframework.transaction.annotation.Transactional;
 import com.core.common.core.domain.R;
 import com.core.common.enums.TenantOptionDict;
 import com.core.common.exception.ServiceException;
@@ -377,6 +378,7 @@ public class AdviceProcessAppServiceImpl implements IAdviceProcessAppService {
      * @return 操作结果
      */
     @Override
+    @Transactional(rollbackFor = Exception.class)
     public R<?> adviceExecute(AdviceExecuteParam adviceExecuteParam) {
         // 实际执行时间
         Date exeDate = adviceExecuteParam.getExeDate();
@@ -804,12 +806,6 @@ public class AdviceProcessAppServiceImpl implements IAdviceProcessAppService {
                     chargeItemService.saveOrUpdate(chargeItem);
                 } else {
                     // 批次售卖情况
-                    // 需要的药品数量(小单位)
-                    BigDecimal minUnitQuantity = medicationRequestUseExe.getMinUnitQuantity();
-                    if (minUnitQuantity == null || minUnitQuantity.compareTo(BigDecimal.ZERO) <= 0) {
-                        throw new RuntimeException("药品执行数量异常，medicationId: "
-                                + finalLongMedicationRequest.getMedicationId());
-                    }
                     // 库存集合
                     List<AdviceInventoryDto> inventoryList = advice.getInventoryList();
                     if (inventoryList == null || inventoryList.isEmpty()) {
@@ -822,9 +818,23 @@ public class AdviceProcessAppServiceImpl implements IAdviceProcessAppService {
                         throw new RuntimeException("未找到药品匹配的定价信息: "
                                 + finalLongMedicationRequest.getMedicationId());
                     }
+                    // 需要的药品数量(小单位)
+                    BigDecimal minUnitQuantity = medicationRequestUseExe.getMinUnitQuantity();
+                    if (minUnitQuantity == null || minUnitQuantity.compareTo(BigDecimal.ZERO) <= 0) {
+                        throw new RuntimeException("药品执行数量异常，medicationId: "
+                                + finalLongMedicationRequest.getMedicationId());
+                    }
+                    // 【修复】预先计算总可用库存，确保在写入任何数据前进行校验
+                    BigDecimal totalAvailableQuantity = inventoryList.stream()
+                            .map(AdviceInventoryDto::getQuantity)
+                            .reduce(BigDecimal.ZERO, BigDecimal::add);
+                    if (totalAvailableQuantity.compareTo(minUnitQuantity) < 0) {
+                        throw new RuntimeException("药品库存不足，medicationId: "
+                                + finalLongMedicationRequest.getMedicationId());
+                    }
                     // 剩余需要分配的数量
                     BigDecimal remainingQuantity = minUnitQuantity;
-                    
+
                     // 按批次循环分配数量
                     for (AdviceInventoryDto inventory : inventoryList) {
                         if (remainingQuantity.compareTo(BigDecimal.ZERO) <= 0) {
@@ -927,11 +937,6 @@ public class AdviceProcessAppServiceImpl implements IAdviceProcessAppService {
                         chargeItem.setTotalPrice(totalPrice); // 总价
                     
                         chargeItemService.saveOrUpdate(chargeItem);
-                    
-                    }
-                    if (remainingQuantity.compareTo(BigDecimal.ZERO) > 0) {
-                        throw new RuntimeException("药品库存不足，medicationId: "
-                                + finalLongMedicationRequest.getMedicationId());
                     }
                 }
             }